INTRACYTOPLASMIC SPERM INJECTION (ICSI) is a very similar fertility treatment to the conventional IVF treatment. The major difference between the IVF and ICSI procedures is the method of achieving fertilization. In conventional IVF procedure, the eggs and sperm are mixed together in a dish and the sperm fertilizes the egg ‘naturally’. Large numbers of actively swimming normal sperms are required to get best results from IVF procedure. But in many couples, the number of suitable sperm is very limited or there can be other factors which prevent fertilization hence conventional IVF treatment is not an effective option. In this case, ICSI procedure plays a crucial role to achieve pregnancy.

Sometimes the sperm cannot penetrate the outer layer due to various reasons. The egg’s outer layer can be thick or hard to penetrate or the sperm is unable to swim. In these cases, Fertility specialist doctor performs a procedure called as Intracytoplasmic Sperm Injection (ICSI). This procedure is performed along with In Vitro Fertilization (IVF) to help fertilize the egg. During ICSI procedure, a single sperm is injected directly into the cytoplasm the egg. Intracytoplasmic Sperm injection (ICSI) involves the direct injection of sperm into eggs which are obtained from in vitro fertilization (IVF). ICSI treatment is very effective to cure male infertility diseases.


We have been performing Intracytoplasmic Sperm injection (ICSI) treatments with a greater success ratio. Our Intracytoplasmic Sperm injection (ICSI) center in Powai provides modern, effective and result oriented IUI, ICSI and IVF treatments to patients. Dr. Rita Modi an Intracytoplasmic Sperm injection (ICSI) specialist in Powai, is helping lots of infertile women and men to become a happy parents.


Need of ICSI treatment

 ICSI treatment is very helpful to overcome infertility problems such as

  • When the sperm count is very low
  • When the sperm cannot move properly
  • When sperm has retrieved surgically from the epididymis (MESA/PESA) or the testes
  • (TESE/TESA), from urine or following electro-ejaculation
  • When there are high levels of antibodies in the semen
  • When there is a previous fertilization failure using conventional IVF

Procedure of ICSI treatment

  • The Intracytoplasmic Sperm injection process takes place during IVF. It is mainly performed for couples who are suffering from male infertility problems and for those couples who did not get desired results from IVF procedure in the past.
  • A sperm sample is taken from partner’s semen or surgically extracted from male partner’s testes or epididymis.
  • Eggs are surgically extracted from woman’s ovaries.
  • Then a tiny needle called as micropipette is used to inject a single sperm into the center of the egg.
  • After injection, the fertilized egg is observed for growth and development.
  • Once ICSI treatment completes and fertilization occurs, embryo grows in a laboratory for 1 to 5 days.
  • Finally, after the confirmation of normal growth of embryo then it is transferred to the woman’s uterus (womb).
  • The fertility specialist uses blood testor ultrasound to determine whether implantation and pregnancy has occurred or not.

ICSI and Male Infertility

ICSI treatment is very beneficial to treat male infertility issues. Most common Male infertility problems include

  • Absence of sperm in the semen
  • Low sperm count, poor sperm quality, abnormal sperm shape and movement
  • Sperm unable to penetrate through the outer layer of egg or production of antisperm antibodies

Side Effects of ICSI treatment

ICSI fertilizes 50% to 80% of eggs. But various problems can occur during or after the ICSI process including

  • Some or all of the eggs can be damaged.
  • The egg doesn’t grow into an embryo even after it is injected with sperm.
  • The embryo can stop growing.

Once fertilization takes place, a couple’s chance of giving birth to a single baby, twins or triplets is the same if they have IVF with or without ICSI procedure. Couple should consult the doctor in detail about ICSI procedure to avoid complications in the future. ICSI procedure is becoming more common in IVF treatment because it increases the chances of sperm penetration into eggs.

Our Intracytoplasmic Sperm injections (ICSI) center in Powai offers an advanced fertility test and treatment procedure. Dr Rita Modi an Intracytoplasmic Sperm injection (ICSI) specialist in Powai, is dedicated in providing specially personalized treatment options. Our expert quality care and professional approach help us to achieve the highest pregnancy and live birth rates.